Searchable abstracts of presentations at key conferences in endocrinology

ea0098b20 | Basic Science | NANETS2023

Establishment of novel PDXovo models for gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs)

Kulathunga Nilakshi , Mar Sara , Wang Zoey , Qureshi Areeba , Tsui Hubert , Hallet Julie , Law Calvin , Leong Hon S. , Michael Iacovos P.

Background: Neuroendocrine cancers arise in the endocrine cells localized throughout the body. Most are found in the Gastroenteropancreatic (GEP) system pancreas, stomach, and small and large intestines. They are heterogenous in their etiology, morphology, and phenotypes. Due to late diagnosis and low prevalence, clinical specimens are limited for research. Thus, preclinical models are pivotal for the understanding of this disease. This study focuses on establishing a novel pa...